|Full Name||solute carrier family 10 (sodium/bile acid cotransporter family), member 2|
|Product Description||Rabbit Polyclonal antibody to ASBT|
|Background||This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]|
|Synonyms||NTCP2 Antibody, IBAT Antibody, solute carrier family 10 (sodium/bile acid cotransporter family), member 2 Antibody, PBAM Antibody, SLC10A2 Antibody, ISBT Antibody|
|Immunogen||The immunogen is within the range 178-195a.a (Human).|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.