|Full Name||thyroid hormone receptor interactor 4|
|Product Description||Rabbit Polyclonal antibody to ASC1 (thyroid hormone receptor interactor 4)|
|Background||Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function. |
|Synonyms||ASC-1 antibody, HsT17391 antibody, TRIP4 antibody, TR-interacting protein 4 antibody, activating signal cointegrator 1 antibody, TRIP-4 antibody, thyroid receptor interacting protein 4 antibody, thyroid receptor-interacting protein 4 antibody, thyroid hormone receptor interactor 4 antibody|
|Cellular Localization||Nucleus , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ASC1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (85%), Rhesus Monkey (98%), Bovine (87%)|