Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||25 kDa (note)
|Positive Controls||U87-MG , SK-N-SH , IMR32 , SK-N-AS , SH-SY5Y , SH-SY5Y nuclear extract , PC-12 , Rat2|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||achaete-scute complex homolog 1 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to ASCL1 (achaete-scute complex homolog 1 (Drosophila))|
|Background||This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq]|
|Synonyms||bHLHa46 Antibody , MASH1 Antibody , HASH1 Antibody , achaete-scute complex homolog 1 (Drosophila) Antibody , ASH1 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ASCL1. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (84%)|