|Full Name||asialoglycoprotein receptor 1|
|Product Description||Rabbit Polyclonal antibody to ASGPR1 (asialoglycoprotein receptor 1)|
|Background||Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. [provided by RefSeq]|
|Synonyms||ASGPR antibody, ASGPR1 antibody, CLEC4H1 antibody, HL-1 antibody, ASGR1 antibody, asialoglycoprotein receptor 1 antibody, hepatic lectin H1 antibody, C-type lectin domain family 4 member H1 antibody|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ASGPR1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (82%)|