|Full Name||amiloride-sensitive cation channel 2, neuronal|
|Product Description||Rabbit Polyclonal antibody to ASIC1 (amiloride-sensitive cation channel 2, neuronal)|
|Background||This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown. Alternative splicing of this gene generates 2 transcript products. [provided by RefSeq]|
|Synonyms||ASIC antibody, ASIC1 antibody, ASIC1A antibody, BNaC2 antibody, hBNaC2 antibody, ACCN2 antibody, acid-sensing ion channel 1a protein antibody, brain sodium channel 2 antibody, ACCN2 variant 3 antibody, "Cation channel, amiloride-sensitive, neuronal, 2 antibody", "amiloride-sensitive cation channel 2, neuronal antibody", acid-sensing ion channel 1 antibody|
|Cellular Localization||Cell membrane; Multi-pass membrane protein , Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ASIC1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (97%), Rhesus Monkey (100%), Bovine (99%)|