|Full Name||ankyrin repeat, SAM and basic leucine zipper domain containing 1|
|Product Description||Rabbit Polyclonal antibody to ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1)|
|Background||Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation. |
|Synonyms||ALP1 Antibody, GASZ Antibody, CT1.19 Antibody, ankyrin repeat, SAM and basic leucine zipper domain containing 1 Antibody, ANKL1 Antibody, Orf3 Antibody, C7orf7 Antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ASZ1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Cat, Rabbit, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Human (100%), Rat (84%), Cat (89%), Rabbit (89%), Sheep (86%), Rhesus Monkey (97%), Chimpanzee (99%), Bovine (87%)|