|Full Name||activating transcription factor 4 (tax-responsive enhancer element B67)|
|Product Description||Rabbit Polyclonal antibody to ATF4 (activating transcription factor 4 (tax-responsive enhancer element B67))|
|Background||This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. [provided by RefSeq]|
|Synonyms||CREB-2 antibody, CREB2 antibody, TAXREB67 antibody, TXREB antibody, ATF4 antibody, DNA-binding protein TAXREB67 antibody, cyclic AMP-responsive element-binding protein 2 antibody, cAMP-responsive element-binding protein 2 antibody, cAMP response element-binding protein 2 antibody, tax-responsive enhancer element-binding protein 67 antibody, cyclic AMP-dependent transcription factor ATF-4 antibody, cAMP-dependent transcription factor ATF-4 antibody, activating transcription factor 4 (tax-responsive enhancer element B67) antibody|
|Cellular Localization||Cytoplasm , Cell membrane , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ATF4. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Pig, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (83%), Pig (89%), Sheep (87%), Rhesus Monkey (97%), Chimpanzee (99%), Bovine (86%)|