|Full Name||autophagy related 16-like 1 (S. cerevisiae)|
|Product Description||Rabbit Polyclonal antibody to ATG16L1 (autophagy related 16-like 1 (S. cerevisiae))|
|Background||Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).[supplied by OMIM]|
|Synonyms||ATG16L Antibody, WDR30 Antibody, APG16L Antibody, IBD10 Antibody, autophagy related 16-like 1 (S. cerevisiae) Antibody, ATG16A Antibody|
|Cellular Localization||Cytoplasm , Preautophagosomal structure membrane; Peripheral membrane protein , Cytoplasm , Preautophagosomal structure membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ATG16L1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (93%), Pig (92%), Rhesus Monkey (80%), Bovine (94%)|