|Full Name||ATG4 autophagy related 4 homolog B (S. cerevisiae)|
|Product Description||Rabbit Polyclonal antibody to ATG4B (ATG4 autophagy related 4 homolog B (S. cerevisiae))|
|Background||Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Synonyms||APG4B antibody, AUTL1 antibody, MGC1353 antibody, ATG4B antibody, autophagy-related cysteine endopeptidase 1 antibody, hAPG4B antibody, APG4 autophagy 4 homolog B antibody, autophagin-1 antibody, autophagy-related protein 4 homolog B antibody, AUT-like 1 cysteine endopeptidase antibody, cysteine protease ATG4B antibody, ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ATG4B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (91%), Rat (91%), Pig (91%), Bovine (86%)|