|Full Name||5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase|
|Product Description||Rabbit Polyclonal antibody to ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase)|
|Background||This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]|
|Synonyms||AICAR antibody, AICARFT antibody, FLJ93545 antibody, IMPCHASE antibody, PURH antibody, ATIC antibody, bifunctional purine biosynthesis protein PURH antibody, AICARFT/IMPCHASE antibody, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase antibody, AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme antibody, 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase antibody, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ATIC. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Chicken, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (92%), Pig (92%), Chicken (83%), Bovine (93%)|