| Full Name | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| Background | This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14. [provided by RefSeq] |
| Synonyms | ATP5C antibody, ATP5CL1 antibody, ATP5C1 antibody, F-ATPase gamma subunit antibody, mitochondrial ATP synthase, gamma subunit 1 antibody, ATP synthase subunit gamma, mitochondrial antibody, ATP synthase gamma chain, mitochondrial antibody, ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 antibody |
| Cellular Localization | Mitochondrion , Mitochondrion inner membrane |
| Validated Note | Knockdown/Knockout validation was supported by references (PMID:26990993) |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ATP synthase gamma. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse, Rat |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Bovine |
| Predict Reactivity Note | Bovine (86%) |
| Conjugation | Unconjugated |