|Full Name||ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c|
|Product Description||Rabbit polyclonal antibody to ATP6V0C (ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c)|
|Background||This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L. [provided by RefSeq]|
|Synonyms||ATP6C antibody, ATP6L antibody, ATPL antibody, VATL antibody, VPPC antibody, Vma3 antibody, ATP6V0C antibody, vacuolar ATP synthase 16 kDa proteolipid subunit antibody, V-ATPase 16 kDa proteolipid subunit antibody, "H(+)-transporting two-sector ATPase, 16 kDa subunit antibody", vacuolar proton pump 16 kDa proteolipid subunit antibody, vacuolar H+ ATPase proton channel subunit antibody, V-type proton ATPase 16 kDa proteolipid subunit antibody, "ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c antibody"|
|Cellular Localization||Vacuole membrane; Multi-pass membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATP6V0C. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Xenopus laevis, Chicken, Sheep, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (100%), Rat (100%), Xenopus laevis (100%), Chicken (100%), Sheep (100%), Bovine (100%)|