|Full Name||ataxin 7-like 3|
|Product Description||Rabbit Polyclonal antibody to ATXN7L3 (ataxin 7-like 3)|
|Background||Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. |
|Synonyms||DKFZp761G2113 antibody, ATXN7L3 antibody, SAGA-associated factor 11 homolog antibody, ataxin-7-like protein 3 antibody, ataxin 7-like 3 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ATXN7L3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Zebrafish, Bovine|
|Predict Reactivity Note||Mouse (100%), Zebrafish (86%), Bovine (99%)|