|Full Name||AXL receptor tyrosine kinase|
|Product Description||Rabbit Polyclonal antibody to AXL (AXL receptor tyrosine kinase)|
|Background||The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||JTK11 antibody, UFO antibody, AXL antibody, AXL oncogene antibody, tyrosine-protein kinase receptor UFO antibody, oncogene AXL antibody, AXL transforming sequence/gene antibody, AXL receptor tyrosine kinase antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human AXL. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig|
|Predict Reactivity Note||Mouse (97%), Rat (97%), Pig (98%)|