|Full Name||acetyl-CoA carboxylase alpha|
|Product Description||Rabbit Polyclonal antibody to Acetyl CoA Carboxylase 1 (acetyl-CoA carboxylase alpha)|
|Background||Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||ACAC antibody , ACACA antibody , ACACAD antibody , ACC antibody , ACC1 antibody , ACCA antibody , Acetyl CoA Carboxylase 1 antibody , Acetyl CoA Carboxylase 1 antibody , acetyl-CoA carboxylase alpha antibody|
|Target||Acetyl CoA Carboxylase 1|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Acetyl CoA Carboxylase 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Chicken, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Pig (94%), Chicken (83%), Sheep (94%), Rhesus Monkey (98%), Bovine (94%)|