Aconitase 2 antibody [N1N3]
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||85 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , JurKat , Mouse brain , rat brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||aconitase 2, mitochondrial|
|Product Description||Rabbit Polyclonal antibody to Aconitase 2 (aconitase 2, mitochondrial)|
|Background||The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq]|
|Synonyms||ACONM antibody, MGC20605 antibody, MGC33908 antibody, ACO2 antibody, citrate hydro-lyase antibody, "aconitate hydratase, mitochondrial antibody", "aconitase 2, mitochondrial antibody"|
|Cellular Localization||Mitochondrion |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Aconitase 2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Chicken, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (91%), Xenopus laevis (94%), Pig (98%), Rhesus Monkey (98%), Bovine (97%)|