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Catalog Number
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GTX47938
(
0
)
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Product Name
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Actinomycin D (Ready-to-Use)
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| Full Name | Apoptosis-Inducing Chemical Actinomycin D (1000X) |
| Synonyms | Dactinomycin, Apoptosis Inducer, Actinomycin C1, Actinomycin IV |
| Product Description | Apoptosis-Inducing Chemical Actinomycin D (1000X) |
| Background | A small molecule that acts as an antineoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells. A potent inducer of apoptosis in many cell lines |
| Applications | CC, Control |
| Application Note | We recommend using 1000X dilutions for inducing apoptosis in Jurkat cells (e.g., Add 1 uL to 1 ml of culture medium). However, the optimal doses may vary for different cells and culture conditions. |
| Form Supplied | Liquid |
| Purity | >98% pure, as determined by TLC |
| Concentration | 10
mM
(Please refer to the vial label for the specific concentration) |
| Storage Buffer | In DMSO (10 mM) |
| Storage Instruction | Store at -20°C. Protect from light and moisture. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |