|Full Name||activin A receptor, type IC|
|Product Description||Rabbit Polyclonal antibody to Activin A Receptor Type IC (activin A receptor, type IC)|
|Background||ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM]|
|Synonyms||ACVRLK7 antibody, ALK7 antibody, ACVR1C antibody, ALK-7 antibody, activin receptor type IC antibody, ACTR-IC antibody, activin receptor-like kinase 7 antibody, activin receptor type-1C antibody, "activin A receptor, type IC antibody"|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Activin A Receptor Type IC. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (94%), Rhesus Monkey (99%), Bovine (97%)|