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Catalog Number
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GTX111737
(
0
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Product Name
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Adenylate kinase 2 antibody [N1C3-2]
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| Applications | ICC/IF, IHC-P, WB |
| Application Note |
| Suggested dilution | Reference |
| Immunocytochemistry/ Immunofluorescence (ICC/IF) | 1:100-1:1000* |
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| IHC (Formalin-fixed paraffin-embedded sections) | 1:100-1:1000* |
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| Western Blot (WB) | 1:500-1:3000* |
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Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Target Size | 26 kDa (note)
 (7)
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| Positive Controls | 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain |
| Form Supplied | Liquid |
| Concentration | 1
mg/ml
(Please refer to the vial label for the specific concentration) |
| Purification | Purified by antigen-affinity chromatography. |
| Full Name | adenylate kinase 2 |
| Background | Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq] |
| Synonyms | ADK2 antibody, AK 2 antibody, AK2 antibody, ATP-AMP transphosphorylase 2 antibody, "adenylate kinase 2, mitochondrial antibody", "adenylate kinase isoenzyme 2, mitochondrial antibody", adenylate kinase 2 antibody |
| Cellular Localization | Mitochondrion intermembrane space |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Adenylate kinase 2. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse, Rat |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Rhesus Monkey, Bovine |
| Predict Reactivity Note | Rhesus Monkey (100%), Bovine (95%) |
| Conjugation | Unconjugated |