Adenylate kinase 2 antibody [N1C3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||26 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||adenylate kinase 2|
|Product Description||Rabbit Polyclonal antibody to Adenylate kinase 2 (adenylate kinase 2)|
|Background||Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]|
|Synonyms||ADK2 antibody, AK 2 antibody, AK2 antibody, ATP-AMP transphosphorylase 2 antibody, "adenylate kinase 2, mitochondrial antibody", "adenylate kinase isoenzyme 2, mitochondrial antibody", adenylate kinase 2 antibody|
|Cellular Localization||Mitochondrion intermembrane space |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Adenylate kinase 2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus Tropicalis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (81%), Xenopus Tropicalis (81%), Rhesus Monkey (100%), Bovine (93%)|