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1 .GTX23455 Adiponectin antibody

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Adiponectin antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsICC/IF, IHC, IP, WB
  • Species reactivityHuman, Mouse, Rat
  • Publication  ( 2 )
Cat No: GTX23455
Package Price Qty
200 μgUSD 319.00
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  • Anti-Adiponectin antibody used in Western Blot (WB). GTX23455
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    Reference (2)
  • Application Information: Adiponectin antibody

Catalog Number GTX23455
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( 0 )
Publication ( 2 )
Product Name Adiponectin antibody
See all Adiponectin products
ApplicationsICC/IF, IHC, IP, WB
Application NoteRecommended Starting Dilutions:
WB: 1:2500 Optimal dilution / concentration should be determined by the end user.
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationProtein A affinity purified

  • Specifications: Adiponectin antibody

Full Nameadiponectin, C1Q and collagen domain containing
BackgroundAdipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin and adiponectin protein of 30 kDa. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation, mRNA levels of Adiponectin have been shown to be induced over 100-fold. Studies indicate that Adiponectin enhances the ability of sub-physiological levels of insulin to suppress glucose production, thus linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol-3-kinase (PI3-K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. mRNA levels of Adiponectin have been shown to be significantly reduced in adipose tissue of obese patients with Type 2 diabetes relative to control subjects. Structural similarities to TNFalpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Because Adiponectin is down-regulated in various forms of obesity and its structural similarity to TNFalpha, it is currently being investigated as an important regulator of whole body energy homeostasis.
SynonymsAdipoq, adipo, Acrp30, Acdc, GBP28, apM1, 30kDa, 11450
HostRabbit
ClonalityPolyclonal
ImmunogenSynthetic peptides corresponding to the residues E(18) D D V T T T E E L A P A L V(32) and F(187) T Y D Q Y Q E K N V D Q A(200) of mouse Adiponectin.
Antigen SpeciesMouse
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: Adiponectin antibody

Storage BufferPBS containing 1mg/ml BSA and 0.05% sodium azide.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Disease Related > Alzheimer's disease
  • Disease Related > Diabetes
  • Metabolism > Fatty acid beta-oxidation
  • Metabolism > Carbonhydrate metabolism > Gluconeogenesis
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Adiponectin antibody validated data
  • Anti-Adiponectin antibody used in Western Blot (WB). GTX23455
    • GTX23455 WB Image
      Western blot of Acrp30 on mouse serum.

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  • Anti-Adiponectin antibody used in Western Blot (WB). GTX23455
    • GTX23455 WB Image
      Western blot of Acrp30 on mouse serum.

      Top
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  • Reference for Adiponectin antibody
Application References Application Reactivity
Martinez-Huenchullan SF et al. Differential metabolic effects of constant moderate versus high intensity interval training in high-fat fed mice: possible role of muscle adiponectin. Physiol Rep 6 (4) (2018). WB Mouse
Harada N et al. Hypogonadism alters cecal and fecal microbiota in male mice. Gut Microbes (Epub ahead of print) (2016). WB Mouse
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All products are for research use only—Not for use in diagnostic procedures.