Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||250 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Product Description||Rabbit polyclonal antibody to Aggrecan (aggrecan)|
|Background||This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq]|
|Synonyms||AGC1 antibody, AGCAN antibody, CSPG1 antibody, CSPGCP antibody, MSK16 antibody, SEDK antibody, ACAN antibody, cartilage-specific proteoglycan core protein antibody, large aggregating proteoglycan antibody, chondroitin sulfate proteoglycan core protein 1 antibody, aggrecan core protein antibody, aggrecan antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Aggrecan. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (96%), Dog (97%), Pig (96%), Bovine (94%)|