Aldolase B antibody
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||39 kDa (note)
|Positive Controls||293T , A431 , Jurkat , Raji , mouse liver , PC-12 , Rat2|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||aldolase B, fructose-bisphosphate|
|Product Description||Rabbit Polyclonal antibody to Aldolase B (aldolase B, fructose-bisphosphate)|
|Background||Fructose-1,6-bisphosphate aldolase (EC 22.214.171.124) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq]|
|Synonyms||ALDB antibody, ALDO2 antibody, ALDOB antibody, fructose-bisphosphate aldolase B antibody, aldolase 2 antibody, aldolase B, fructose-bisphosphatase antibody, liver-type aldolase antibody, aldolase B, fructose-bisphosphate antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Aldolase B. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Rabbit, Chicken, Sheep, Bovine|
|Predict Reactivity Note||Zebrafish (82%), Rabbit (98%), Chicken (84%), Sheep (93%), Bovine (94%)|