|Product Description||Rabbit Polyclonal antibody to Amphiphysin (amphiphysin)|
|Background||This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. [provided by RefSeq]|
|Synonyms||AMPH1 antibody, AMPH antibody, amphiphysin antibody, amphiphysin I antibody, amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen) antibody|
|Cellular Localization||Cytoplasmic vesicle , secretory vesicle , synaptic vesicle membrane , Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Amphiphysin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Pig, Chicken, Bovine|
|Predict Reactivity Note||Xenopus laevis (84%), Pig (100%), Chicken (94%), Bovine (100%)|