|Full Name||islet amyloid polypeptide|
|Product Description||Rabbit polyclonal antibody to Amylin (islet amyloid polypeptide)|
|Background||Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq]|
|Synonyms||DAP antibody, IAP antibody, IAPP antibody, diabetes-associated peptide antibody, amylin antibody, Islet amyloid polypeptide (diabetes-associated peptide, amylin) antibody, islet amyloid polypeptide antibody, insulinoma amyloid peptide antibody|
|Cellular Localization||Secreted |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Amylin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (81%)|