|Full Name||angiopoietin-like 4|
|Product Description||Rabbit polyclonal antibody to Angiopoietin-like 4|
|Background||This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq]|
|Synonyms||ANGPTL2 antibody, ARP4 antibody, FIAF antibody, HFARP antibody, NL2 antibody, PGAR antibody, pp1158 antibody, ANGPTL4 antibody, angiopoietin-related protein 4 antibody, hepatic fibrinogen/angiopoietin-related protein antibody, PPARG angiopoietin related protein antibody, angiopoietin-like protein 4 antibody, peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein antibody, fasting-induced adipose factor antibody, hepatic angiopoietin-related protein antibody, angiopoietin-like 4 antibody, ARP4 antibody|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Angiopoietin-like 4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Sheep, Bovine|
|Predict Reactivity Note||Pig (83%), Sheep (83%), Bovine (83%)|