|Full Name||angiotensinogen (serpin peptidase inhibitor, clade A, member 8)|
|Product Description||Rabbit Polyclonal antibody to Angiotensinogen (angiotensinogen (serpin peptidase inhibitor, clade A, member 8))|
|Background||The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq]|
|Synonyms||ANHU antibody, FLJ92595 antibody, FLJ97926 antibody, SERPINA8 antibody, AGT antibody, angiotensin II antibody, angiotensinogen antibody, serpin A8 antibody, angiotensin I antibody, serine (or cysteine) proteinase inhibitor antibody, "alpha-1 antiproteinase, antitrypsin antibody", pre-angiotensinogen antibody, "angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Angiotensinogen. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (99%)|