|Full Name||ankyrin 1, erythrocytic|
|Product Description||Goat polyclonal antibody to Ankyrin 1 / ANK1|
|Background||Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions. Isoform Mu17 together with obscurin in skeletal muscle may provide a molecular link between the sarcoplasmic reticulum and myofibrils. |
|Synonyms||ANK1, Ankyrin1 / ANK1, ankyrin1, ankyrin-R, ankyrinR, SPH1, ankyrin 1, erythrocytic, ANK, SPH2, ankyrin1, erythrocytic, ankyrin-1, erythrocytic, Ankyrin 1 / ANK1, ankyrin 1, ankyrin R|
|Cellular Localization||Probably the other erythrocyte (Er) isoforms, are located near the surface of erythrocytic plasma membrane. Colocalizes with OBSCN isoform 3/obscurin at the M line in differentiated skeletal muscle cells. |
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Bovine|