| Full Name | serpin peptidase inhibitor, clade C (antithrombin), member 1 |
| Background | The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 12 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq] |
| Synonyms | ATIII, PRO0309, AntithrombinIII, Antithrombin-III, SERPINC1, AT3, Antithrombin III |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human SERPINC1. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse |
| Conjugation | Unconjugated |