|Full Name||serpin peptidase inhibitor, clade C (antithrombin), member 1|
|Product Description||Rabbit Polyclonal antibody to Antithrombin III (antithrombin-III)|
|Background||The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq]|
|Synonyms||AT3 antibody, ATIII antibody, MGC22579 antibody, SERPINC1 antibody, serpin C1 antibody, antithrombin III antibody, antithrombin-III antibody, serine-cysteine proteinase inhibitor clade C member 1 antibody, "serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 antibody", "serpin peptidase inhibitor, clade C (antithrombin), member 1 antibody"|
|Cellular Localization||Secreted , extracellular space |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Antithrombin III. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Sheep, Rhesus Monkey, Bovine, Guinea pig|
|Predict Reactivity Note||Mouse (88%), Rat (86%), Pig (87%), Sheep (86%), Rhesus Monkey (91%), Bovine (84%), Guinea pig (85%)|