|Full Name||anaphase promoting complex subunit 11|
|Product Description||Rabbit polyclonal antibody to Apc11 (APC11 anaphase promoting complex subunit 11 homolog (yeast))|
|Background||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.|
|Synonyms||APC11 antibody, Apc11p antibody, MGC882 antibody, ANAPC11 antibody, anaphase-promoting complex subunit 11 antibody, APC11 anaphase promoting complex subunit 11 homolog antibody, cyclosome subunit 11 antibody, anaphase promoting complex subunit 11 (yeast APC11 homolog) antibody, hepatocellular carcinoma-associated RING finger protein antibody, anaphase promoting complex subunit 11 antibody|
|Cellular Localization||Cytoplasm , Nucleus|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Apc11. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Rhesus Monkey (100%), Bovine (100%)|