|Full Name||apoptosis enhancing nuclease|
|Product Description||Rabbit polyclonal antibody to Apoptosis-enhancing nuclease (apoptosis enhancing nuclease)|
|Background||Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.|
|Synonyms||FLJ12484 antibody, FLJ12562 antibody, ISG20L1 antibody, pp12744 antibody, AEN antibody, interferon-stimulated 20 kDa exonuclease-like 1 antibody, apoptosis-enhancing nuclease antibody, interferon stimulated exonuclease gene 20kDa-like 1 antibody, apoptosis enhancing nuclease antibody|
|Cellular Localization||Nucleus , nucleolus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Apoptosis-enhancing nuclease. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (83%), Rat (83%)|