|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||41 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Product Description||Rabbit Polyclonal antibody to Aprataxin (aprataxin)|
|Background||This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. [provided by RefSeq]|
|Synonyms||AOA antibody, AOA1 antibody, AXA1 antibody, EAOH antibody, EOAHA antibody, FHA-HIT antibody, FLJ20157 antibody, MGC1072 antibody, APTX antibody, forkhead-associated domain histidine triad-like protein antibody, aprataxin antibody|
|Cellular Localization||Nucleus , nucleoplasm , nucleolus |
|Immunogen||Full length human Aprataxin Recombinant protein.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (81%), Dog (91%), Pig (90%), Rhesus Monkey (97%), Bovine (89%)|