|Full Name||arylsulfatase G|
|Product Description||Rabbit polyclonal antibody to Arylsulfatase G (arylsulfatase G)|
|Background||Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors. [provided by RefSeq]|
|Synonyms||KIAA1001 antibody, ARSG antibody, ASG antibody, arylsulfatase G antibody|
|Cellular Localization||Endoplasmic reticulum|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Arylsulfatase G. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Bovine|
|Predict Reactivity Note||Mouse (82%), Rat (82%), Dog (88%), Bovine (85%)|