|Full Name||ectonucleotide pyrophosphatase/phosphodiesterase 2|
|Product Description||Rabbit Polyclonal antibody to Autotaxin (ectonucleotide pyrophosphatase/phosphodiesterase 2)|
|Background||The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||ATX antibody, ATX-X antibody, AUTOTAXIN antibody, FLJ26803 antibody, LysoPLD antibody, NPP2 antibody, PD-IALPHA antibody, PDNP2 antibody, ENPP2 antibody, ectonucleotide pyrophosphatase/phosphodiesterase family member 2 antibody, phosphodiesterase I/nucleotide pyrophosphatase 2 antibody, E-NPP 2 antibody, plasma lysophospholipase D antibody, autotaxin-t antibody, extracellular lysophospholipase D antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Autotaxin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chicken (80%), Bovine (92%)|