|Full Name||v-raf murine sarcoma viral oncogene homolog B1|
|Product Description||Rabbit polyclonal antibody to B-Raf (v-raf murine sarcoma viral oncogene homolog B1)|
|Background||This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq]|
|Synonyms||B-RAF1 antibody, BRAF1 antibody, FLJ95109 antibody, MGC126806 antibody, MGC138284 antibody, NS7 antibody, RAFB1 antibody, BRAF antibody, B-Raf proto-oncogene serine/threonine-protein kinase (p94) antibody, murine sarcoma viral (v-raf) oncogene homolog B1 antibody, 94 kDa B-raf protein antibody, p94 antibody, proto-oncogene B-Raf antibody, serine/threonine-protein kinase B-raf antibody, v-raf murine sarcoma viral oncogene homolog B1 antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human B-Raf. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chicken (89%)|