|Full Name||actin-like 6B|
|Product Description||Rabbit Polyclonal antibody to BAF53B (actin-like 6B)|
|Background||The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. [provided by RefSeq]|
|Synonyms||ACTL6 antibody, BAF53B antibody, ACTL6B antibody, hArpN alpha antibody, arpNalpha antibody, actin-like protein 6B antibody, actin-related protein Baf53b antibody, BRG1-associated factor 53B antibody, actin-like 6 antibody, 53 kDa BRG1-associated factor B antibody, actin-like 6B antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human BAF53B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (99%), Rhesus Monkey (100%), Bovine (99%)|