|Full Name||BCL2-associated athanogene 2|
|Product Description||Rabbit Polyclonal antibody to BAG2 (BCL2-associated athanogene 2)|
|Background||BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]|
|Synonyms||BAG-2 antibody, KIAA0576 antibody, MGC149462 antibody, dJ417I1.2 antibody, BAG2 antibody, BAG family molecular chaperone regulator 2 antibody, BAG-family molecular chaperone regulator-2 antibody, bcl-2-associated athanogene 2 antibody, dJ417I1.2 (BAG-family molecular chaperone regulator 2) antibody, BCL2-associated athanogene 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human BAG2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (95%), Rhesus Monkey (99%), Bovine (95%)|