|Full Name||BAI1-associated protein 2-like 1|
|Product Description||Rabbit Polyclonal antibody to BAIAP2L1 (BAI1-associated protein 2-like 1)|
|Background||This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq]|
|Synonyms||FLJ42275 antibody, IRTKS antibody, BAIAP2L1 antibody, brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 antibody, BAI1-associated protein 2-like protein 1 antibody, insulin receptor tyrosine kinase substrate antibody, BAI1-associated protein 2-like 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human BAIAP2L1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (94%), Rat (94%)|