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1 .GTX84837 BAT1 antibody [2C5]

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BAT1 antibody [2C5]


  • Host / ClonalityMouse Monoclonal
  • Clone Name2C5
  • ApplicationsIHC-P, WB
  • Species reactivityHuman
Cat No: GTX84837
Package Price Qty
100 μlUSD 379.00
Add to cart
 
  • Anti-BAT1 antibody [2C5] used in Western Blot (WB). GTX84837
  • Anti-BAT1 antibody [2C5] used in IHC (Formalin-fixed paraffin-embedded sections). GTX84837
  • Anti-BAT1 antibody [2C5] used in IHC (Formalin-fixed paraffin-embedded sections). GTX84837
  • Anti-BAT1 antibody [2C5] used in IHC (Formalin-fixed paraffin-embedded sections). GTX84837
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  • Datasheet
  • Application Information: BAT1 antibody [2C5]

Catalog Number GTX84837
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Product Name BAT1 antibody [2C5]
See all BAT1 products
ApplicationsIHC-P, WB
Application NoteRecommended Starting Dilutions:

WB 1:500
IHC 1:50,
Optimal working dilutions should be determined experimentally by the end user.

Form SuppliedLiquid
PurificationProtein A/G purified

  • Specifications: BAT1 antibody [2C5]

Full NameDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
BackgroundComponent of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4. Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint. Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity. Even with the stimulation of RNA, the ATPase activity is weak. Can only hydrolyze ATP but not other NTPs. The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA. However, ssRNA stimulates the ATPase activity much more strongly than dsRNA. Can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro. The ATPase and helicase activities are not influenced by U2AF2 and THOC4.
SynonymsD6S81E
SpecificityGTX84837 is specific for human BAT1(NP_542165).
HostMouse
ClonalityMonoclonal
Clone Name2C5
IsotypeIgG2b
ImmunogenFull length human recombinant protein of human BAT1(NP_542165) produced in HEK293T cell.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: BAT1 antibody [2C5]

Storage BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage InstructionFor short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C (aliquotted). Avoid repeated freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Disease Related > Alzheimer's disease
  • Disease Related > Cardiovascular > Heart > Heart disease
  • Disease Related > Diabetes
  • Immunology > Autoimmunity > Autoimmune diseases > Diabetes
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BAT1 antibody [2C5] validated data
  • Anti-BAT1 antibody [2C5] used in Western Blot (WB). GTX84837
    • GTX84837 WB Image
      HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BAT1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BAT1.
      Top
  • Anti-BAT1 antibody [2C5] used in IHC (Formalin-fixed paraffin-embedded sections). GTX84837
    • GTX84837 IHC-P Image
      Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-BAT1 mouse monoclonal antibody. (GTX84837, Dilution 1:50)
      Top
  • Anti-BAT1 antibody [2C5] used in IHC (Formalin-fixed paraffin-embedded sections). GTX84837
    • GTX84837 IHC-P Image
      Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-BAT1 mouse monoclonal antibody. (GTX84837, Dilution 1:50)
      Top
  • Anti-BAT1 antibody [2C5] used in IHC (Formalin-fixed paraffin-embedded sections). GTX84837
    • GTX84837 IHC-P Image
      Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-BAT1 mouse monoclonal antibody. (GTX84837, Dilution 1:50)
      Top
  • Anti-BAT1 antibody [2C5] used in Western Blot (WB). GTX84837
    • GTX84837 WB Image
      HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BAT1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BAT1.
      Top
  • Anti-BAT1 antibody [2C5] used in IHC (Formalin-fixed paraffin-embedded sections). GTX84837
    • GTX84837 IHC-P Image
      Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-BAT1 mouse monoclonal antibody. (GTX84837, Dilution 1:50)
      Top
  • Anti-BAT1 antibody [2C5] used in IHC (Formalin-fixed paraffin-embedded sections). GTX84837
    • GTX84837 IHC-P Image
      Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-BAT1 mouse monoclonal antibody. (GTX84837, Dilution 1:50)
      Top
  • Anti-BAT1 antibody [2C5] used in IHC (Formalin-fixed paraffin-embedded sections). GTX84837
    • GTX84837 IHC-P Image
      Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-BAT1 mouse monoclonal antibody. (GTX84837, Dilution 1:50)
      Top
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