BCL6 antibody [N2C1], Internal
|Applications||IHC-P, IP, WB, ChIP assay|
Not tested in other applications.
| ChIP assay||Assay-dependent dilution
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||79 kDa (note)
|Positive Controls||Jurkat , Raji , NCI-H929 , Neuro2A , GL261 , C8D30 , NIH-3T3 , Raw264.7 , C2C12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||B-cell CLL/lymphoma 6|
|Product Description||Rabbit Polyclonal antibody to BCL6 (B-cell CLL/lymphoma 6)|
|Background||The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||BCL5 antibody, BCL6A antibody, LAZ3 antibody, ZBTB27 antibody, ZNF51 antibody, BCL6 antibody, B-cell lymphoma 6 protein antibody, lymphoma-associated zinc finger gene on chromosome 3 antibody, zinc finger transcription factor BCL6S antibody, B-cell lymphoma 6 protein transcript antibody, zinc finger and BTB domain-containing protein 27 antibody, protein LAZ-3 antibody, cys-his2 zinc finger transcription factor antibody, B-cell lymphoma 5 protein antibody, BCL-5 antibody, BCL-6 antibody, zinc finger protein 51 antibody, B-cell CLL/lymphoma 6 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human BCL6. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (92%), Dog (90%), Pig (89%), Rhesus Monkey (97%), Bovine (90%)|