|Full Name||Bcl2 modifying factor|
|Product Description||Rabbit Polyclonal antibody to BMF (Bcl2 modifying factor)|
|Background||The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||FLJ00065 antibody, BMF antibody, bcl-2-modifying factor antibody, Bcl2 modifying factor antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human BMF. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (87%), Rat (87%), Bovine (91%)|