|Full Name||bone morphogenetic protein 4|
|Product Description||Rabbit Polyclonal antibody to BMP4 (bone morphogenetic protein 4)|
|Background||The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq]|
|Synonyms||BMP2B antibody, BMP2B1 antibody, MCOPS6 antibody, OFC11 antibody, ZYME antibody, BMP4 antibody, BMP-2B antibody, bone morphogenetic protein 4 antibody, bone morphogenetic protein 2B antibody, BMP-4 antibody|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human BMP4. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Dog, Pig, Rabbit, Chicken, Sheep, Bovine|
|Predict Reactivity Note||Rat (98%), Zebrafish (88%), Xenopus laevis (95%), Dog (99%), Pig (99%), Rabbit (98%), Chicken (93%), Sheep (98%), Bovine (99%)|