|Full Name||bone morphogenetic protein receptor, type IA|
|Product Description||Rabbit Polyclonal antibody to BMPR1A (bone morphogenetic protein receptor type-1A)|
|Background||The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq]|
|Synonyms||10q23del antibody, ACVRLK3 antibody, ALK3 antibody, CD292 antibody, SKR5 antibody, BMPR1A antibody, activin receptor-like kinase 3 antibody, BMPR-1A antibody, BMP type-1A receptor antibody, "activin A receptor, type II-like kinase 3 antibody", ALK-3 antibody, bone morphogenetic protein receptor type-1A antibody, serine/threonine-protein kinase receptor R5 antibody, "bone morphogenetic protein receptor, type IA antibody"|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human BMPR1A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Dog, Pig, Chicken, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (98%), Xenopus laevis (86%), Dog (99%), Pig (100%), Chicken (95%), Sheep (99%), Rhesus Monkey (100%), Bovine (98%)|