BPGM antibody [N1C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||30 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , Molt-4 , Raji , mouse spleen|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||2,3-bisphosphoglycerate mutase|
|Product Description||Rabbit Polyclonal antibody to BPGM (2,3-bisphosphoglycerate mutase)|
|Background||2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]|
|Synonyms||BPGM antibody, "erythrocyte 2,3-bisphosphoglycerate mutase antibody", "2,3-diphosphoglycerate mutase antibody", "2,3-bisphosphoglycerate synthase antibody", bisphosphoglycerate mutase antibody, BPG-dependent PGAM antibody, "2,3-bisphosphoglycerate mutase, erythrocyte antibody", "2,3-bisphosphoglycerate mutase antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human BPGM. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rabbit, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (92%), Rabbit (97%), Chicken (81%), Rhesus Monkey (98%), Chimpanzee (99%), Bovine (94%)|