|Full Name||3'(2'), 5'-bisphosphate nucleotidase 1|
|Product Description||Rabbit Polyclonal antibody to BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1)|
|Background||BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq]|
|Synonyms||PIP antibody, BPNT1 antibody, bisphosphate 3'-nucleotidase 1 antibody, BPntase antibody, "PAP-inositol-1,4-phosphatase antibody", "3'(2'),5'-bisphosphate nucleotidase 1 antibody", "3'(2'), 5'-bisphosphate nucleotidase 1 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Rat (94%), Xenopus laevis (84%), Chicken (83%), Bovine (93%)|