BRG1 antibody [GT2712]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||185 kDa (note)
|Positive Controls||K562 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12 , Rat2|
(Please refer to the vial label for the specific concentration)|
|Purification||Affinity purified by Protein G.|
|Full Name||SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4|
|Product Description||Mouse Monoclonal antibody [GT2712] to BRG1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4)|
|Background||The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||BAF190 antibody , BAF190A antibody , BRG1 antibody [GT2712] antibody , BRG1 antibody , MRD16 antibody , RTPS2 antibody , SMARCA4 antibody , SNF2 antibody , SNF2L4 antibody , SNF2LB antibody , SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 antibody , SWI2 antibody , hSNF2b antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human BRG1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chicken (83%), Bovine (85%)|