|Full Name||Bruton agammaglobulinemia tyrosine kinase|
|Product Description||Rabbit Polyclonal antibody to BTK (Bruton agammaglobulinemia tyrosine kinase)|
|Background||The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq]|
|Synonyms||AGMX1 antibody, AT antibody, ATK antibody, BPK antibody, IMD1 antibody, MGC126261 antibody, MGC126262 antibody, PSCTK1 antibody, XLA antibody, BTK antibody, dominant-negative kinase-deficient Brutons tyrosine kinase antibody, agammaglobulinaemia tyrosine kinase antibody, B-cell progenitor kinase antibody, tyrosine-protein kinase BTK isoform (lacking exon 14) antibody, tyrosine-protein kinase BTK antibody, Bruton agammaglobulinemia tyrosine kinase antibody|
|Cellular Localization||Cytoplasm , Membrane; Peripheral membrane protein , Nucleus , Cytoplasm , Membrane , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human BTK. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Bovine|
|Predict Reactivity Note||Rat (98%), Pig (99%), Chicken (86%), Bovine (98%)|