|Full Name||Bruton agammaglobulinemia tyrosine kinase|
|Product Description||Rabbit Polyclonal antibody to BTK (Bruton agammaglobulinemia tyrosine kinase)|
|Background||The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq]|
|Synonyms||Bruton agammaglobulinemia tyrosine kinase Antibody , ATK Antibody , PSCTK1 Antibody , BPK Antibody , AGMX1 Antibody , IMD1 Antibody , XLA Antibody , AT Antibody|
|Cellular Localization||Cytoplasm , Membrane; Peripheral membrane protein , Nucleus , Cytoplasm , Membrane , Nucleus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BTK. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Pig (100%), Bovine (100%)|