Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||122 kDa (note)
|Positive Controls||293T , A431 , H1299 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||budding uninhibited by benzimidazoles 1 homolog (yeast)|
|Product Description||Rabbit Polyclonal antibody to BUB1 (budding uninhibited by benzimidazoles 1 homolog (yeast))|
|Background||This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer. [provided by RefSeq]|
|Synonyms||BUB1A antibody, BUB1L antibody, hBUB1 antibody, BUB1 antibody, mitotic spindle checkpoint kinase antibody, BUB1 budding uninhibited by benzimidazoles 1 homolog antibody, putative serine/threonine-protein kinase antibody, mitotic checkpoint serine/threonine-protein kinase BUB1 antibody, budding uninhibited by benzimidazoles 1 homolog (yeast) antibody|
|Cellular Localization||Nucleus , Kinetochore |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human BUB1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (80%)|